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Department of Pathology & Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; Department of Medicine, Division of Hematology/Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC; Department of Biostatistics and North Carolina Translational and Clinical Sciences Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC; Departamento de Cirurgia, North Carolina Jaycee Burn Center, University of North Carolina at Chapel Hill, Chapel Hill, NC; Departamento de Cirurgia, Division of Trauma and Critical Care Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC.