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Del Centre for Critical Illness, Lawson Research Health Research Institute (AX, HH, XL, ICY, QF), Canadian Blood Services (ICY), y Departamentos de Medicina (AX, HH, ICY, QF) y Fisiología y Farmacología (QF), University of Western Ontario, London, Ontario, Canadá; North Sichuan Medical College First Affiliated Hospital (HH), Nanchong, Sichuan, R.P. China.